A loxP site was inserted 200 bp upstream of exon 1 and a floxed and FRT flanked neo cassette was inserted 600 bp downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:182665)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count