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The RPCI24-6817 bacterial artificial chromosome (BAC) was modified by introduction of a cre-recombinase gene within the first exon of the activation-induced cytidine deaminase (Aicda) gene. This 190 kb BAC transgene contains the modified AID-Cre gene, as well as Dpp3, Gdf3, Apobec, and Mfap5. This transgene was microinjected into the pronuclei of fertilized FVB/NCrl oocytes. A single founder was used to establish the line. (J:125740)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
