A loxP site was inserted into the BsaHI site in intron 1, and a loxP site and a FRT-flanked neomycin cassette was inserted into the XcmI site in intron 6. Flp-mediated recombination removed the neo cassette. (J:148648)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count