The Emu enhancer and Igh promoter drives late pro-B cell-specific expression of the mouse microRNA followed by the 3'UTR and polyadenylation sequence from the human beta-globin gene. Eight founders were established generating several lines (lines 8 through 15). Northern blot analysis confirmed transcript expression in the spleen. (J:109591)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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