The targeting vector contains loxP site inserted upstream of exon 1 and a FRT-flanked NEO cassette followed by a second loxP site downstream of exon 6. Cre-mediated recombination removed the neo cassette and exons 1-6. (J:241631)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count