A targeting vector was designed with a loxP-flanked neomycin resistance cassette, an internal ribosome entry site (IRES), and an enhanced yellow fluorescent protein (eYFP) sequence. This vector was inserted downstream of the endogenous translational stop codon and upstream of the 3' untranslated region (UTR). Cre-mediated recombination removed the neo cassette. (J:147784)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
Insertion
--
1
7
77

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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