An FRT-flanked promoterless cassette, which contains a splice acceptor, beta-geo and polyadenylation sequence, with a 3' loxP site was inserted upstream of exon 4. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the promoterless cassette and left exon 4 floxed. (J:182628)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count