A floxed neomycin selection cassette was inserted in intron 2 and a third loxP site was place upstream of exon 2 in intron 1. The selection cassette was subsequently removed as a result of cre expression leaving exon 2 flanked by loxP sites. (J:182000)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count