A targeting vector containing a ubiquitin C promoter, floxed stop cassette, human cDNA encoding a constituitively active form, and a floxed neo cassette was inserted into the locus. Cre-mediated recombination removed the neo cassette. (J:182287)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count