This reciprocal translocation was found by fertility screening of progeny of male mice exposed to 600 rad X-rays to the hind part of the body and mated immediately afterward, during the pre-sterile period. Analysis of giemsa- (G-) banded chromosomes placed the cytological breakpoints at bands 7B3 and 19D1. The genetic breakpoints were determined by duplication-deletion mapping to lie between Gpi1 and Oca2 on Chr 7 and between Papss2 and Hps6 on Chr 19. (J:5959, J:34742)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C3H/HeH x 101/H)F1
Radiation induced
Translocation
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--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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