Cre-mediated recombination removed the neo cassette and the microRNA cluster stem loop from Mirc13tm1Mtm. qRT-PCR analysis confirmed the loss of the microRNA. Beta-galactosidase expression is observed in lung and olfactory bulb in late embryonic stages. (J:181752, J:256444)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intergenic deletion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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