Log In|Sign Up
EN
A cassette containing Hoxd11-IRES2-nlslacZ was inserted into the Gt(ROSA)26Sor locus via homologous recombination in YFP3.1 ES cells. The inserted cassette has a floxed PGK-neo STOP sequence preceding it, preventing Hoxd11 or lacZ transcription unless cre-mediated excision of the STOP has taken place. Targeted ES cells were injected into C57BL/6J blastocysts. This line was maintained on a C57BL/6J background. (J:137524)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
