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The transgene comprises, in order, a 1.3 kb fragment of the mouse myelin basic protein (Mbp) gene that includes the promoter, mRNA cap site and 5' noncoding sequence; a mouse Mbp cDNA containing the full coding sequence for the smallest (14kDa) MBP protein; the 760 bp third exon of the mouse prion protein (Prnp) gene - which contains the entire Prnp open reading frame - flanked by two copies of the rabbit beta-globin second intron; and polyadenylation signals from the rabbit beta-globin and SV40 early region genes. (J:97275)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
