A T cell line (designated C6.9-VP2) was isolated from the spinal cords of Theiler's murine encephalomyelitis virus (TMEV, BeAn strain) infected SJL/J mice that specifically recognizes the TMEV capsid protein peptide VP274-86. Based on this cell line, a transgenic strain that expresses the VP2-specific regulatory T cell receptor was created. Line 1 was generated. (J:146452)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
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Insertion
--
--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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