A construct was designed by replacing the C-terminal glycosylphosphatidyl inositol (GPI) anchor signal with a myc tag and cloned into the cos.Tet vector. The cos.Tet vector is a cosmid-based expression vector derived from the Syrianhamster prion protein (Prnp) gene. Line 8015 was generated. (J:180145)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB.129S7(B6)-Prnptm1Cwe/J
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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