A construct was designed by replacing the C-terminal glycosylphosphatidyl inositol (GPI) anchor signal with a myc tag and cloned into the cos.Tet vector. The cos.Tet vector is a cosmid-based expression vector derived from the Syrianhamster prion protein (Prnp) gene. Line 8015 was generated. (J:180145)
Basic Information
FVB.129S7(B6)-Prnptm1Cwe/J
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count