Sufu^b2b273Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to A substitution at coding nucleotide 530 in exon 4 of the cDNA (c.530T>A, NM_001025391). This changes the methionine residue to lysine at position 177 of the encoded protein (p.M177K). Additional incidental mutations were detected in sequencing for the causative mutation, Sufub2b273Clo, and may be present in stocks carrying this mutation.