A floxed inverted MC1-neo cassette was inserted upstream of exon 6 and a loxP site was inserted downstream of exon 7 via homologous recombination. Cre mediated recombination removed the neo cassette leaving exons 6 and 7 floxed. (J:181294)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count