This transgene expresses the mouse cardiac alpha-actin with a histidine substitution for an arginine at amino acid 312 (R312H) and an HA tag under the control of the murine alpha-myosin heavy chain promoter. Three lines were made, with line 307 the highest expressor. (J:178587)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count