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The transgene consists of a 1600 bp DNA fragment containing the promoter of the mouse whey acidic protein gene joined to nucleotides 1372-1822 of the hepatitis B virus (subtype group ayw) genome, encoding the HBV-x protein, followed by a DNA fragment encoding the FLAG epitope tag (DYKDDDDF). Expression of the transgene is detected by northern and western blot analysis and is demonstrated by RT-PCR analysis to correspond to that of the endogenous whey acidic protein gene during pregnancy, lactation and post-lactation involution of the mammary epithelial tissue. (J:83717)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
