A Venus reporter and floxed neo cassette was inserted at the translation initiation site. Cre-mediated recombination removed the neo cassette. Flow cytometry confirmed the absence of protein expression in cultured Th2+ cells stimulated with PMA and ionomycin or anti-CD3 antibodies. (J:180790)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count