A Venus reporter and floxed neo cassette was inserted at the translation initiation site. Cre-mediated recombination removed the neo cassette. Flow cytometry confirmed the absence of protein expression in cultured Th2+ cells stimulated with PMA and ionomycin or anti-CD3 antibodies. (J:180790)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion
--
1
--
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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