A targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette upstream of exon 4. Cre-mediated recombination removed the neo cassette. (J:181311)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count