A targeting vector was designed to insert a loxP site upstream of exon 5, followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 6 of the a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 (Adamts18) gene. (J:181091)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count