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Exon 3 was flanked with loxP sites. Deletion of exon 3 by cre excision caused loss of function by removing part of the organic anion transporter domain and generating a frameshift from exon 2 to exon 4-11 followed by a premature stop at codon 52. PCR analysis confirmed the removal of exon 3 in mRNA. (J:180950)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
