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The transgene was designed with the 441 bp mouse SM22alpha (transgelin; Tagln) promoter fragment upstream of a mouse tissue factor pathway inhibitor (Tfpi) cDNA sequence encoding the TFPIalpha isoform (TFPIalpha is the predominant TFPI protein isoform in humans). Mice with the highest expression of transgenic TFPI mRNA were identified (founder line 1661). (J:180949)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
