A fusion of human DTR and EGFP, an IRES sequence, and a self excising Cre-Neo cassette were inserted in the 3' untranslated region via homologous recombination. Plasmacytoid dendritic cells from homozygous mice are deficient in transcriptional and cell surface expression. (J:179283)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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