A fusion of human DTR and EGFP, an IRES sequence, and a self excising Cre-Neo cassette were inserted in the 3' untranslated region via homologous recombination. Plasmacytoid dendritic cells from homozygous mice are deficient in transcriptional and cell surface expression. (J:179283)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count