Nucleotide substitutions (CCC to TCG) result in the amino acid substitution of serine for proline at position 224 (P224S). This mutation is equivalent to one found in long-lived isp-1 (qm150) worms. Flp-mediated recombination removed the neo cassette used for selection purposes. (J:179765)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion, Nucleotide substitutions
--
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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