Log In|Sign Up
EN
The transgene comprises a 10-kb HindIII restriction fragment of genomic DNA from the C57BL/6 (haplotype H2b) mouse strain containing the entire, eight-exon major histocompatibility (MHC) class I H2-D gene, more than 4 kb of 5' flanking DNA including the promoter and all known regulatory sequences, and approximately 1 kb of 3' flanking DNA. Activated peripheral blood lymphocytes of transgenic mice stain with a monoclonal antibody specific for H-2Db and H2-Kb proteins. (FVB is of the H2q haplotype.) (J:18556)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
