246 bp of intron 1, exon 1, exon 2, and intron 2 was replaced with a tau-lacZ and floxed neo cassette. Western blot analysis confirmed the absence of protein expression in the hippocampus, cortex, and cerebellum. (J:179026)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count