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Mobilization of the transposon from TgTn(sb-SBlac)CFsp transgenic mice with Sleeping Beauty transposase from an unidentified line of TgTn(sb-SBlac)15Fsp transgenic mice results in the integration of the transposon at chr2:73958058-73958059 (GRCm39) in reverse (tel-cen) orientation. This location is in the gene desert between Atp5g3 and Lnp. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. LacZ expression is detected in the distal limbs and genital bud of E11.5 embryos. (J:180121)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
