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A transgene construct containing 3.5 kb of sequence upstream of the ATG start site of the mouse Krt8 gene (purified from BAC clone RP23-254K21), the beta globin intron, SV40 polyadenylation site and a cre/ERT2 segment was injected into C57Bl/6 fertilized eggs. Four of seven founder mice displayed the expected pattern of expression and Founder line 17 was subsequently established. The transgenic animals were then bred to CD1 mice. (J:180048)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
