An IRES-creERT cassette, together with an FRT flanked PGK-neo cassette, were inserted into the 3' UTR. The neo selection cassette was subsequently excised by crossing to mice expressing flp recombinase. (J:180047, J:182218)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count