Germ line, cre mediated recombination was used to remove the neo cassette leaving exons 5 and 6 flanked by loxP sites. Liver specific deletion of the two floxed exons eliminates protein product in the liver. (J:140089, J:179193)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count