Exon 2, containing the transcription start codon was replaced by lacZ and a floxed neomycin and Tk selection cassette. The selection cassette was subsequently excised from properly targeted ES cells. (J:179478)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count