The J1, J2, and J3 regions were replaced with a rearranged human light chain sequence of the HIV-1 broadly neutralizing antibody (bnAb) 2F5 and a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:179317)
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The J1, J2, and J3 regions were replaced with a rearranged human light chain sequence of the HIV-1 broadly neutralizing antibody (bnAb) 2F5 and a floxed neo cassette. Cre-mediated recombination removed the neo cassette. (J:179317)