RMCE on KH2 ES cells introduced an shRNA targeting Rsp19 behind a tetracycline responsive element into the 3'UTR. The level of knock down by this allele following doxycycline treatment is higher compared to mice expressing Col1a1tm1(tetO-RNAi:Rps19)Karl . (J:179085)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count