An FRT-flanked neo cassette with a 5' loxP site is inserted upstream of exon 11. An additional loxP site was inserted downstream of exon 11. Cre-mediated recombination removed the neo cassette and exon 11. (J:178550)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count