A loxP site was inserted upstream of exon 1. A floxed neo cassette with a 3' EGFP gene was inserted downstream of exon 1. Cre-mediated recombination removed the neo cassette and left exon 1 floxed followed by the EGFP gene. (J:178164)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count