The hTDP-43 transgene was designed with the mouse prion protein (Prnp) promoter driving expression of a mutant form of the human TARDBP gene modified to have the methionine to valine substitution at codon 337 (M337V). Line 4 was generated. (J:179348)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count