An FRT-flanked neo cassette with loxP site was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 1. The neo cassette was removed by flp-mediated recombination. (J:180431)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count