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The mouse mammary gland tumor virus (MMTV) promoter drives mammary gland-specific expression of a tetracycline transactivator (tTA). Two lines were generated (25754 and 25755). Line 25754 integrated on chromosome 8 (chr8:12,485,790-12,564,686; mouse mm10), approximately 10kb upstream of the Spaca7 locus. Currently there are no genes annotated in the integration region. This analysis also identified the transgene includes an SV40 NLS and polyA signal. (J:178842)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
