A loxP site was inserted upstream of the coding sequence in exon 1, a loxP site, EGFP, FRT-flanked neomycin resistance cassette were inserted downstream of the coding sequence in exon 3. Flp-mediated recombination removed the selection cassette and left the coding sequence floxed and the EGFP reporter intact. (J:207801)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count