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The 3.3 kbp PGK2-SB10-SV40 transgene was designed with the 1.4 kbp human phosphoglycerol kinase 2 promoter (PGK2) sequence, the coding sequence for the SB10 Sleeping Beauty transposase, and the SV40 early region intron/polyA signal. The SB10 gene is a majority-rule consensus sequence (engineered to eliminate the inactivating mutations from a Tc1-like element transposase gene of the salmonid subfamily) encoding the 340 amino acid synthetic, putative transposase gene. Line 1780 was generated. (J:178892)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
