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The promoter drives liver-specific expression of the human cDNA with a poly A signal derived from the human growth hormone and alpha-fetoprotein enhancer elements. Lines E (one insertion on chromosome 3H3) and G (one insertion on chromosome XA6) were generated. Line E does not elicite an antibody response while line G elicites the highest level of antibody response. Protein expression is detected in various organs but not in the circulation. (J:176909)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
