Homologous recombination inserted an FRT-flanked neo cassette followed by an loxP site downstream of exon 2. An additional loxP site inserted upstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:176532)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count