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A hemagglutinin tagged human FOXO4 DNA containing T28A, S193A, and S258A mutations was placed under the control of the Fabp4 promoter. Four positive lines were analyzed for protein expression and one un-named line which was positive by Western blot analysis was backcrossed for at least 7 generations to C57BL/6J. Expression of the transgene was detected in brown adipose tissue, all white adipose tissue depots and in macrophages. (J:178134)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
