Foxj1^b2b774Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to A substitution at coding nucleotide 425 in exon 2 of the cDNA (c.425T>A, NM_008240). This changes the isoleucine residue to asparagine at position 142 in the encoding protein (p.I142N). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Foxj1b2b774Clo, and may be present in stocks carrying this mutation.