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The original OT-I transgenic constructs were obtained from F. Carbone (University of Melbourne, Melbourne, Victoria, Australia). The OT-Ialpha chain was tagged on the C terminus with a 20-aa flexible linker and a single enhanced GFP using standard molecular cloning techniques and was expressed under the CD4 enhancer and promoter without the silencer. The OT-Ibeta chain was expressed under its endogenous promoter. (J:177978)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
