The mouse open reading frame (exon 2 through 9) was replaced with the human gene from BAC RPCI-11, clone 101M23. A floxed neo cassette inserted downstream of the human sequence was removed by cre-mediated recombination. (J:177073)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(BALB/cJ x 129S4/SvJae)F1
Targeted
Insertion
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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