The mouse open reading frame (exon 2 through 9) was replaced with the human gene from BAC RPCI-11, clone 101M23. A floxed neo cassette inserted downstream of the human sequence was removed by cre-mediated recombination. (J:177073)
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The mouse open reading frame (exon 2 through 9) was replaced with the human gene from BAC RPCI-11, clone 101M23. A floxed neo cassette inserted downstream of the human sequence was removed by cre-mediated recombination. (J:177073)