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A 7 kb fragment of genomic DNA containing 4 kb of upstream sequence and 3 kb downstream of the ATG site of the Musahi 1 (Msi1) gene promoter was used drive the cre recombinase sequence in a transgenic construct. Transgenic mice were produced in a C57BL/6 x CBA hybrid background. in crosses to reporter animals, mice demonstrate cre activity in tissues such as brain, skin, lung and more specifically in the bottom of intestinal crypts. (J:177631)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
