The wild-type sequence of intron 1 of Zeb1 and the predicted gene Gm10125, a loxP site, and IRES-lacZ cassette, and a floxed inverted pgk-neo cassette were inserted via homologous recombination. Cre mediated recombination removed the IRES-lacZ and pgk-neo cassettes. (J:177274)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count